لنفوم peripheral T-cell-not otherwise specified اولیه پانکراس با تظاهر پانکراتیت حاد: گزارش مورد و مروری بر متون
کد: G-1013
نویسندگان: Fatemeh Zari Meidani ℗, Rahem Rahmati ©, Elahe Meftah, Maryam Soheilipour
زمان بندی: جمعه ۱۴۰۲/۰۹/۱۷ ۱۰:۳۰ بر روی یونیت Panel A
دانلود: دانلود پوستر
خلاصه مقاله:
خلاصه مقاله
Primary pancreatic lymphoma (PPL) is an extremely rare extra-nodal lymphoid malignancy. An uncommon histological subtype of PPL is Peripheral T-cell lymphoma (PTCL). Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) is a rare, highly aggressive subgroup of PTCL with a poor prognosis. The least common presentation of PTCL-NOS is extra-nodal, including the pancreas. Pancreatic lymphoma symptoms, such as pancreatitis, are often heterogeneous and can mimic those of other pancreatic diseases like adenocarcinoma, making the diagnosis even more challenging. We report a 35-year-old female with a recent history of pancreatitis, jaundice, and intermittent epigastric and left-upper-quadrant abdominal pain. The radiological evaluation revealed a mass in the head, neck, and body of the pancreas, and following an open biopsy, the tumor was diagnosed as PTCL-NOS. The patient did not recover after six cycles of cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisone (CHOP) chemotherapy and revealed CNS involvement in the follow-up. PPL is a rare malignant neoplasia with a challenging diagnosis regarding its nonspecific clinical features. Histopathologic evaluation is important in the differential diagnosis of clinicopathologic subtypes regarding their different prognoses and therapeutic methods. Due to the possibility of CNS involvement in the setting of PTCL-NOS, healthcare providers should also consider neurological assessment for a proper follow-up.
کلمات کلیدی
Pancreatitis; Pancreatic adenocarcinoma; Pancreatic lymphoma; T-cell lymphoma-not otherwise specified.
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