Esophageal leiomyoma and simultaneous overlying squamous cell carcinoma

Mohammad Javad Yavari Barhaghtalab © ℗, Saadat Mehrabi, Safoora Hejazinia

Esophageal leiomyoma and simultaneous overlying squamous cell carcinoma

Code: G-1024

Authors: Mohammad Javad Yavari Barhaghtalab © ℗, Saadat Mehrabi, Safoora Hejazinia

Schedule: Friday 2023-12-08 10:30 on Unit Panel C

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Abstract:

Abstract

Squamous cell carcinoma is the most common epithelial tumor of the esophagus. Upper endoscopy with multiple minimally invasive biopsies should be performed to confirm the diagnosis. Leiomyoma of the esophagus is rare, but it’s the most common benign submucosal mesenchymal tumor of the esophagus. The simultaneous occurrence of an overlying epithelial lesion and a mesenchymal lesion is very rare. This study aims to show a case operated due to squamous cell carcinoma of the esophagus that was postoperatively diagnosed with coexistent esophageal leiomyoma and give a clear overview of the existing literature on it. The patient was a 41-year-old woman who underwent three field esophagectomy (McKeown). Pathological evaluation was done, and the patient had poorly differentiated squamous cell carcinoma and multiple leiomyomas. A leiomyoma was found with an invading overlying squamous cell carcinoma. It is concluded that esophageal carcinomas may coexist with leiomyomas; preexisting benign tumors may have played an important role in the development of the carcinoma by inducing constant stimulation of the overlying mucosa; endoscopic ultrasonography is recommended to avoid overestimating the extent of tumor invasion and the resultant aggressive radical surgery. As the developing countries had limited equipment, esophageal resection could be the modality of choice in the treatment.

Keywords

Esophageal squamous cell carcinoma, Leiomyoma, Simultaneous occurrence, Esophagectomy, Case report, Literature review

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