ارزیابی اپیدمیولوژیک متاپلازی های روده ای و عفونت با هلیکوباکتر پیلوری در شیراز، ایران: طراحی مدل پیشگویی کننده وقوع متاپلازی

ارزیابی اپیدمیولوژیک متاپلازی های روده ای و عفونت با هلیکوباکتر پیلوری در شیراز، ایران: طراحی مدل پیشگویی کننده وقوع متاپلازی

کد: G-1053

نویسندگان: Mohammadali Moghimizadeh, Mansoureh Shokripour, Aref Hafezi Bafti ℗, Navid Omidifar ©

زمان بندی: جمعه ۱۴۰۲/۰۹/۱۷ ۱۰:۴۵ بر روی یونیت Panel A

برچسب:

دانلود: دانلود پوستر

خلاصه مقاله:

خلاصه مقاله

H.pylori is classified as a group 1 carcinogenic in classification by the World Health Organization This bacterium plays a role in the development of various pathologies including gastric carcinoma, and mucosa-associated lymphoid tissue (MALT) lymphoma. Considering the high prevalence of infection with this pathogen and the strong and direct relationship between long-term infection with this bacterium and the development of gastrointestinal tract malignancies, the importance of studying this issue becomes more prominent. Method: In this Cross-Sectional study we obtained our data from pathology reports of Gastric samples from 2021 to 2023 in Faghihi hospital, Shiraz, Iran. We used SPSS V26 for performing Chi-Square and Fischer’s exact test analysis of Categorical Data And Bivariate logistic regression to create statistical models for predicting metaplasia and Occult bleeding chances. Result: 1954 cases entered our study. A meaningful difference between the male gender and a higher incidence of metaplasia was seen but There is no significant statistical difference between H.pylori in gender groups. male gender causes a 259% increase in the possibility of having a positive OB test. Also, each year that life passes by, the probability of positive OB increases by 2%. The biggest effect (standardized beta:1.45) belonged to the amount of inflammation present in the stomach mucosa. Moderate to severe and mild inflammation had an increased chance of positive OB by 427% and 42% respectively. male gender and each increasing age are positively correlated with metaplasia occurrence at 40% and 3% respectively. Also, the severity of gastritis is a very powerful predictive factor for predicting metaplasia. (10 times more) Although H.pylori eradication regimes and non-invasive tests are available universally and in Iran still the prevalence of active H.pylori infection and active severe gastritis are high and significant. Also, the high correlation between gastritis and positive OB puts this great number of patients at risk of chronic IDA. The most important relation we want to emphasize is the enormous effect of Gastritis severity as a modifiable factor (in contrast with age and sex) on developing metaplasia in patients. Better policy-making and Follow-up protocols are the keys to the door of preventing GI malignancies.

کلمات کلیدی

Helicobacter pylori, intestinal metaplasia, intestinal gastritis, gastric cancer, occult blood, statistical modeling

ارسال دیدگاه توسط مدیریت بسته شده است.